Searchable abstracts of presentations at key conferences in endocrinology

ea0032p372 | Diabetes | ECE2013

Association between toll-like receptor 4 polymorphism and type 2 diabetes mellitus

Mesci Banu , Eren Pinar , Kiziltas Safak , Oguz Aytekin , Tuncer Ilyas , Kostek Osman , Colak Yasar

Introduction: Type two diabetes (T2DM), is the most common form of diabetes and known to be associated with low-grade inflammation. Since TLR-4 plays an important role in bacteriel recognition of lipopolysaccharide (LPS) and activation of proinflammatory pathways we aimed of to test whether TLR-4 gene polymorphism plays a protective role in the development of T2DM in a pilot Turkish population.Description of methods/design: Blood samples were collected f...